Stephen tells her he will understand if she needs help. Jane, focusing on the children as well as Stephen's health and increasing fame, is unable to work on her own thesis and becomes frustrated.

After the Hawkings have their daughter Lucy, Stephen develops a theory about the visibility of black holes and becomes a world-renowned physicist. He begins using a wheelchair after his walking ability deteriorates. Stephen presents his thesis to the examination board, arguing that a black hole created the universe in a Big Bang, that it will emit heat, and end in a Big Crunch. They marry and have their first son, Robert. She tells his father she intends to stay with Stephen even as his condition worsens. As Stephen becomes reclusive, focusing on his work, Jane confesses she loves him. The doctor assures Stephen that his brain will not be affected, so his thoughts and intelligence will remain intact, but eventually, he will be unable to communicate them. There are no treatments, and he has approximately two years to live. He learns he has motor neuron disease, which will eventually leave him unable to move, swallow, and even breathe. However, Stephen's muscles begin to fail, giving him decreasing coordination with his body. After he and his professor Dennis Sciama attend a lecture on black holes, Stephen speculates that black holes may have been part of the creation of the universe, and decides to write his thesis on them. Although Stephen is intelligent, his friends and professors are concerned about his lack of a thesis topic. University of Cambridge astrophysics student Stephen Hawking begins a relationship with literature student Jane Wilde. It also received three Screen Actors Guild Awards nominations, and won the Screen Actors Guild Award for Outstanding Performance by a Male Actor in a Leading Role for Redmayne. It received four Golden Globe Award nominations, winning the Golden Globe Award for Best Actor – Motion Picture Drama for Redmayne, and Best Original Score for Jóhannsson. The film received 10 British Academy Film Awards (BAFTA) nominations, and won Outstanding British Film, Best Leading Actor for Redmayne, and Best Adapted Screenplay for McCarten.

The film gained numerous awards and nominations, including five Academy Award nominations: Best Picture, Best Actress (Jones), Best Adapted Screenplay, Best Original Score (Jóhannsson) and won Best Actor for Redmayne. The film received positive reviews, with praise for the musical score, cinematography, and the performances of Jones and especially Redmayne. It had its UK premiere on 1 January 2015. The film had its world premiere at the 2014 Toronto International Film Festival on 7 November 2014. The film stars Eddie Redmayne and Felicity Jones, with Charlie Cox, Emily Watson, Simon McBurney, Christian McKay, Harry Lloyd, and David Thewlis featured in supporting roles. It was adapted by Anthony McCarten from the 2007 memoir Travelling to Infinity: My Life with Stephen by Jane Hawking, which deals with her relationship with her ex-husband Stephen Hawking, his diagnosis of amyotrophic lateral sclerosis (ALS), and his success in the field of physics. Set at the University of Cambridge, it details the life of the theoretical physicist Stephen Hawking. The Theory of Everything is a 2014 biographical romantic drama film directed by James Marsh.

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